- 產品描述
上海嶸崴達實業有限公司,專業經營生命科學領域的科研試劑、儀器和實驗室消耗品,
致力于向國內生命科學研究人員提供*的產品和服務。
我們代理和經銷的分子生物學試劑、生化試劑、免疫試劑、細胞培養試劑、制藥工業原料、實驗儀器與消耗品、臨床診斷產品等,已被廣泛應用于生命科學基礎與開 發研究、制藥、疾病診斷、人口與健康、生物技術等諸多領域。我們的客戶遍布大學、研究所、醫院、制藥公司、生物技術公司等單位。
主要經營的試劑品牌:
Roche試劑,部分常用現貨,周三定貨,2-3周到貨。
GE試劑,耗材,部分常用現貨,周二,周五定貨,3周左右到貨。
R&D試劑,周三定貨,2-3周到貨。
SIGMA試劑,周一,五定貨,3周左右到貨。
Millipore試劑,每周三定貨,2-3周到貨。
Invitrogen試劑,部分現貨,周三定貨,2-3周到貨。
ABCAM試劑,周三定貨,2-3周到貨。
eBioscience試劑,部分常用現貨,周三定貨,2-3周到貨。
STANT CRUZ試劑,周三定貨,2-3周到貨。
Biolegend試劑,周三定貨,2-3周到貨。
Peprotech試劑,部分常用現貨,周三定貨,2-3周到貨。
USB試劑,常備現貨,周五定貨,4周到貨。
Amresco試劑,常備現貨,3-4周到貨。
羅氏原料,請來電來郵咨詢。
Thermo試劑,pierce, Hyclone部分常用現貨。
主要經營的耗材品牌:
1. BIOHIT,單道移液半支消毒長期*,350/支。
2. BD Fa2. BD Falcon耗材,常用常備現貨。
3. BRAND,常備現貨
sigma試劑 Lactoferrin from bovine milk,L9507- ≥85%(SDS-PAGE)
assay | ≥85% (SDS-PAGE) |
mol wt | mol wt ~87 kDa |
storage temp. | 2-8°C |
Gene Information | Research your gene in Your Favorite Gene powered by Ingenuity cow ... LTF(280846) |
描述
Biochem/physiol Actions
Lactoferrin is an iron binding protein. It is structurally similar to transferrin, the plasma iron transport protein; but lactoferrin has a much higher affinity for iron (250 fold). It is very abundant in colostrum and small amounts can also be found in tears, saliva, mucous secretions and in the secondary granules of neutrophils. It is made by mucosal epithelium and neutrophils and is released by these cells in response to inflammatory stimuli. Bacterial growth is inhibited by its ability to sequester iron and also permeabilize bacterial cell walls by binding to lipopolysaccharides through its N-terminus. Lactoferrin can inhibit viral infection by binding tightly to the viral envelope protein. This prevents cell-virus fusion by blocking the binding domain. Lactoferrin appears to activate host defense systems in part by stimulating the release of interleukin-8, a neutrophil activator. It may also be involved in antibody and interleukin synthesis, lymphocyte proliferation and complement activation.